Per vial, USD
| Fill weight | 100+ | 1,000+ | 2,500+ | Order |
|---|---|---|---|---|
| 500 mg | $9.13 | $7.67 | $7.49 | |
| 1000 mg | $24.75 | $20.79 | $20.30 |
Ordering at volume
NAD+ is bought by the gram rather than by the milligram, and that changes everything about the order. The per-vial price tracks the raw material closely, so the 1,000 mg fill is priced near twice the 500 mg fill, and the choice of fill is about vial count and handling convenience rather than about cost. It is held in California as a standard-catalog line, and each fill weight reaches its tier breaks on its own quantity.
Large fills mean real shipping weight. A thousand vials at 1,000 mg is a kilogram of powder plus the far greater mass of the glass, so the freight line on the quote reflects real mass; ask for the carton count and gross weight if a receiving dock has limits. Hygroscopic material should travel with desiccant; confirm at quote how the lot is packed.
Because it is a commodity raw material, lot age matters more than continuity of supply. Ask for the manufacturing date of the lot and for its water content on the certificate, since a lot that has drawn moisture in storage will assay low on a dry basis. A first order should also ask how the vial is closed, since moisture past the closure is the hazard.
Specification
- Compound
- NAD+
- CAS number
- 53-84-9
- Formula
- C₂₁H₂₇N₇O₁₄P₂
- Molecular weight
- 663.4 g/mol
- PubChem CID
- 5892
- Form
- Lyophilized powder, sealed vial
- Fill weights
- 500 mg · 1000 mg
- Stock depth
- Standard catalog — Stocked in California. Each compound reaches its own tier break.
- Intended use
- Laboratory research only. Not for human or veterinary use.
What the material is
NAD+ is nicotinamide adenine dinucleotide in its oxidized state, which is what the plus sign denotes. It is not a peptide. Structurally it is two nucleotides, one carrying nicotinamide and one carrying adenine, joined through a pyrophosphate bridge between their ribose units, with a molecular weight of 663.4 g/mol. The catalog lists it under its full chemical name as well as the abbreviation.
The powder is white to off-white, and at 500 mg and 1,000 mg the vial holds a dry powder rather than a formed cake. The material is hygroscopic and takes on water readily when exposed, becoming sticky and eventually gummy; a free-flowing powder is the sign of a properly packed lot. It is also somewhat sensitive to light and to alkaline conditions, both of which are handling points below.
Storage and reconstitution
Store sealed vials at −20 °C in a dry, dark place, and keep them in their carton, with any desiccant that shipped with them, until needed. NAD+ in the solid state is stable for a long period when kept dry and cold, and the largest risk to a stored lot is moisture, not temperature. Let a vial warm fully before opening so that no condensation forms on the powder.
The powder dissolves freely in water to give a colourless to faintly yellow solution. Solutions in plain water are acidic and are considerably more stable than solutions in neutral or alkaline buffer, where the oxidized dinucleotide degrades appreciably within hours at room temperature. Solutions are best prepared cold, used the same day where possible, and kept out of light.
Portions of the solid are weighed out quickly and the vial resealed, since an opened vial left in humid air will absorb water and clump. Frozen aqueous solutions hold for a limited time and only if the pH is acidic; repeated freeze-thaw cycles are not recommended, and a solution that has turned yellow-brown should be discarded.
Buying questions
Is NAD+ shipped as a lyophilized cake like the peptides?
Not as a formed cake; at 500 mg and 1,000 mg it is a dry powder in the vial. A free-flowing powder is what a good lot looks like, and a vial in which the powder has clumped or gone sticky has taken on moisture and should be reported before anything else in the shipment is unpacked.
How heavy is a 1,000-vial NAD+ order?
Heavier than any peptide order of the same count: a kilogram of powder at the 1,000 mg fill, plus glass, cartons and desiccant. Ask the desk to state cartons and gross weight so a receiving dock can plan for it.
Which is the better fill of NAD+ to order, 500 mg or 1,000 mg?
Cost per gram is close between them, because the raw material sets the price. Take the 500 mg fill where the receiving lab opens a vial and uses part of it over a period, since a smaller opened vial is less exposed to humidity; take the 1,000 mg fill where whole vials are used at once.
Does the NAD+ certificate report water content?
Yes, on request through COA requests; ask for it specifically. Water content matters for a hygroscopic solid because the assay is reported on a dry basis, and the date of manufacture of the lot is worth requesting at the same time.
